Turmeric is undoubtedly one of the most studied plants worldwide. Its healing properties and medicinal components have been the subject of more than 12,000 peer-reviewed studies. As a matter of fact, a 5-year old long research has found that this amazing plant possesses more than 800 preventative and therapeutic applications, and 250 beneficial physiological local effects.
Taking into consideration the amount of research done on this spice, it is no wonder that countless studies have suggested that it compare to a variety of medications, including:
According to a 2008 study published in the journal Drugs in R & D, a standardized preparation of curcuminoids from Turmeric compared to the drug atorvastatin (trade name Lipitor) on endothelial dysfunction, the underlying pathology of the blood vessels which drives atherosclerosis/ in connection to significant reductions in both oxidative stress and inflammation in type 2 diabetic patients.
Corticosteroids (steroid medications)
According to a 1999 study published in the journal Phytotherapy Research, the key polyphenol in turmeric called curcumin, compared favorably to steroids in the management of an inflammatory eye disease called chronic anterior uveitis. Additionally, a 2008 study published in Critical Care Medicine revealed that curcumin compared favorably to the corticosteroid drug dexamethasone in the animal model as an alternative therapy for protecting lung transplantation-associated injury by down-regulating inflammatory genes.
Metformin (diabetes drug)
According to a 2009 study published in the journal Biochemitry and Biophysical Research Community, turmeric stimulates AMPK (which increases glucose uptake) and suppresses gluconeogenic gene expression (which suppresses glucose production in the liver) in hepatoma cells. It was found that curcumin is 500 times to 100,000 times (in the form known as tetrahydrocurcuminoids(THC)) more powerful than metformin in activating AMPK and its downstream target acetyl-CoA carboxylase (ACC).
Oxaliplatin (chemotherapy drug)
According to a 2007 study published in the International Journal of Cancer, curcumin compares favorably with oxaliplatin as an antiproliferative agenet in colorectal cell lines.
Prozac/Fluoxetine & Imipramine (antidepressants):
According to a 2011 study published in the journal Acta Poloniae Pharmaceutica, curcumin compared favorably to Prozac/ Fluoxetine and Imipramine in reducing depressive behavior in an animal model.
Aspirin (blood thinner)
According to a 1986 in vitro and ex vivo study published in the journal Arzneimittelforschung, curcumin has the same anti-platelet and prostacyclin modulating effects as aspirin, suggesting that it may have value in patients prone to vascular thrombosis and requiring anti-arthritis therapy.
According to a 2004 study published in the journal Oncogene, curcumin was effective alternative to the drugs aspirin, ibuprofen, tamoxifen, dexamethasone, celecoxib, indomethacin, sulindac, phenylbutazone, naproxen, and diclofenac in providing anti-inflammatory and anti-proliferative effects against tumor cells.